Biochemistry - MCQ Practice Questions

In the carnitine shuttle system, carnitine palmitoyltransferase I (CPT-I) is inhibited by:

Which of the following conditions would result in elevated levels of lipoprotein(a) (Lp(a))?

A 50-year-old female with hypothyroidism presents with elevated cholesterol. Which mechanism explains the increased cholesterol in hypothyroidism?

The oxidative stress marker oxidized LDL (oxLDL) primarily activates which receptor to promote foam cell formation?

In Type III hyperlipoproteinemia (Familial Dysbetalipoproteinemia), the primary defect involves:

A patient with primary biliary cholangitis shows elevated cholestanol levels. Which enzyme defect is most likely responsible?

During the fed state, acetyl-CoA carboxylase (ACC) is activated by which mechanism?

A deficiency of apolipoprotein B-48 synthesis would primarily affect which lipid transport pathway?

A 35-year-old patient with atherosclerosis has normal LDL cholesterol but elevated lipoprotein(a). Which genetic polymorphism is primarily responsible for high Lp(a) levels?

A patient presents with neurodegenerative symptoms, progressive neuropathy, and xanthomas. Plasma cholestanol and cholestane-3-beta,5-alpha,6-beta-triol levels are markedly elevated. Which genetic defect is most likely?

Tangier disease is associated with deficiency of which protein?

In the condition of hypertriglyceridemia with normal LDL levels, which genetic defect is most likely?

A patient with severely elevated serum triglycerides (>1000 mg/dL) is at immediate risk of: