Biochemistry - MCQ Practice Questions

A clinical test shows high triglycerides and low HDL cholesterol. What metabolic condition might be indicated?

In the mobilization of fatty acids from adipose tissue, which hormone plays the primary regulatory role?

Which of the following conditions results from deficiency of lipoprotein lipase?

What is the net ATP yield from complete oxidation of one molecule of a 16-carbon saturated fatty acid (palmitate)?

Apolipoproteins serve multiple functions in lipid transport. Which apolipoprotein is most important for HDL maturation and cholesterol efflux?

In the synthesis of eicosanoids, what is the first critical step?

A 45-year-old patient presents with xanthomas and corneal arcus. Which lipid abnormality is most consistent with these clinical signs?

Which of the following correctly describes the relationship between LDL particle size and cardiovascular risk?

A patient with Tangier disease shows extremely low HDL levels (<5 mg/dL). This condition results from defective:

In the carnitine shuttle system, carnitine palmitoyltransferase I (CPT-I) is inhibited by:

Which of the following conditions would result in elevated levels of lipoprotein(a) (Lp(a))?

A 50-year-old female with hypothyroidism presents with elevated cholesterol. Which mechanism explains the increased cholesterol in hypothyroidism?

The oxidative stress marker oxidized LDL (oxLDL) primarily activates which receptor to promote foam cell formation?

In Type III hyperlipoproteinemia (Familial Dysbetalipoproteinemia), the primary defect involves:

A patient with primary biliary cholangitis shows elevated cholestanol levels. Which enzyme defect is most likely responsible?

During the fed state, acetyl-CoA carboxylase (ACC) is activated by which mechanism?

A deficiency of apolipoprotein B-48 synthesis would primarily affect which lipid transport pathway?

A 35-year-old patient with atherosclerosis has normal LDL cholesterol but elevated lipoprotein(a). Which genetic polymorphism is primarily responsible for high Lp(a) levels?

A patient presents with neurodegenerative symptoms, progressive neuropathy, and xanthomas. Plasma cholestanol and cholestane-3-beta,5-alpha,6-beta-triol levels are markedly elevated. Which genetic defect is most likely?

Tangier disease is associated with deficiency of which protein?