Biochemistry - MCQ Practice Questions

Which enzyme catalyzes the rate-limiting step of cholesterol synthesis?

Phospholipids differ from triglycerides in that they contain:

A person consumes excessive saturated fats. Which lipoprotein level is most likely to increase?

Which steroid hormone is synthesized from cholesterol in the adrenal cortex?

The process of lipogenesis primarily occurs in which tissue during fed state?

The conversion of acetyl-CoA to malonyl-CoA is inhibited by:

A 35-year-old male presents with recurrent yellow nodules on his elbows and knees with serum cholesterol of 450 mg/dL. What is the most likely diagnosis?

Which lipoprotein has the highest ratio of protein to lipid?

The ketone bodies produced during beta-oxidation are synthesized in which tissue?

What is the primary function of apolipoprotein B-100?

Niemann-Pick disease Type C is characterized by defective intracellular lipid transport due to mutation in genes encoding:

During fed state, the conversion of carbohydrates to fat is promoted by insulin through which mechanism?

Which of the following statements about LCAT (Lecithin-cholesterol acyltransferase) is INCORRECT?

A 45-year-old male presents with xanthomas and corneal arcus. Serum cholesterol is 580 mg/dL. Which lipoprotein is primarily elevated in familial hypercholesterolemia?

Beta-oxidation of a saturated fatty acid with 16 carbons produces how many acetyl-CoA molecules?

Which of the following conditions results in accumulation of sphingomyelins and cholesterol in lysosomes?

Apolipoprotein E exists in three isoforms (E2, E3, E4). Which genotype is associated with the highest risk for Alzheimer's disease?

Which of the following statements about lipoproteins is correct?

A patient presents with eruptive xanthomas, lipemia retinalis, and severe hypertriglyceridemia (>1500 mg/dL). Which lipoprotein fraction is predominantly elevated?

In the conversion of cholesterol to bile acids, which intermediate is formed after 7-alpha-hydroxylation?