Biochemistry - MCQ Practice Questions

What is the maximum number of ATP molecules generated from complete oxidation of one glucose molecule under aerobic conditions?

Which carbohydrate is a non-reducing sugar due to the glycosidic linkage between anomeric carbons of both monosaccharides?

In fructose metabolism, fructose is primarily phosphorylated by which enzyme in the liver?

Which of the following statements is TRUE about the Cori cycle?

A patient presents with lactic acidosis after consuming alcohol. Which enzyme's inhibition by acetaldehyde is primarily responsible for this condition?

Which monosaccharide is the primary carbon source for synthesis of heparin and other glycosaminoglycans?

In the pentose phosphate pathway, which intermediate can directly feed into glycolysis as glyceraldehyde-3-phosphate?

Which enzyme deficiency causes Essential Fructosuria, and why is it clinically benign?

A 6-month-old infant develops hypoglycemia, hepatomegaly, and lactic acidosis after feeding. Genetic testing reveals glucose-6-phosphatase deficiency (Type I Glycogen Storage Disease). Why does this cause lactic acidosis?

Which of the following carbohydrates is a heptose?

In glycogen synthesis, which enzyme transfers glucose from UDP-glucose to the growing glycogen chain?

A competitive athlete is found to have a deficiency in muscle phosphorylase (McArdle disease). During intense exercise, which metabolic consequence is PRIMARY?

Which carbohydrate metabolism enzyme is allosterically inhibited by citrate and ATP but activated by AMP and ADP?

In the glucose transporter classification, which GLUT protein is responsible for INSULIN-DEPENDENT glucose uptake in muscle and adipose tissue?

During starvation lasting 3-5 days, what is the PRIMARY source of glucose for the brain and RBCs?

A patient with hemoglobin C disease (defect in β-globin) shows increased levels of fetal hemoglobin (HbF). Why might elevated HbF reduce hemolysis compared to HbS?

Which monosaccharide is the C2 epimer of glucose?

In the non-oxidative phase of the pentose phosphate pathway, transketolase requires which cofactor?

A 3-year-old child presents with hepatomegaly, growth retardation, and elevated liver transaminases. Enzyme assay shows deficiency of lysosomal acid glucosidase (Pompe disease/GSD Type II). Which carbohydrate accumulates PRIMARILY in lysosomes?

Which enzyme catalyzes the first committed step of glycolysis and is inhibited by its end products ATP and citrate?