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Biochemistry - MCQ Practice Questions

Practice free Biochemistry multiple-choice questions with detailed answers and explanations. Perfect for competitive exam preparation.

278 questions | 100% Free

Q.41Easy

Which of the following lipids is amphipathic in nature and forms the structural basis of cell membranes?

Q.42Medium

A 45-year-old male presents with xanthomas and corneal arcus. Serum cholesterol is 580 mg/dL. Which lipoprotein is primarily elevated in familial hypercholesterolemia?

Q.43Medium

Beta-oxidation of a saturated fatty acid with 16 carbons produces how many acetyl-CoA molecules?

Q.44Medium

Which of the following conditions results in accumulation of sphingomyelins and cholesterol in lysosomes?

Q.45Medium

Apolipoprotein E exists in three isoforms (E2, E3, E4). Which genotype is associated with the highest risk for Alzheimer's disease?

Q.46Easy

Which of the following fatty acids is essential and must be obtained from dietary sources?

Q.47Hard

A patient with primary biliary cholangitis shows elevated cholestanol levels. Which enzyme defect is most likely responsible?

Q.48Hard

During the fed state, acetyl-CoA carboxylase (ACC) is activated by which mechanism?

Q.49Medium

Which of the following statements about lipoproteins is correct?

Q.50Medium

A patient presents with eruptive xanthomas, lipemia retinalis, and severe hypertriglyceridemia (>1500 mg/dL). Which lipoprotein fraction is predominantly elevated?

Q.51Easy

Which of the following factors would increase the fluidity of a cell membrane?

Q.52Medium

In the conversion of cholesterol to bile acids, which intermediate is formed after 7-alpha-hydroxylation?

Q.53Hard

A deficiency of apolipoprotein B-48 synthesis would primarily affect which lipid transport pathway?

Q.54Easy

Which of the following lipids serves as a precursor for the synthesis of steroid hormones and bile acids?

Q.55Hard

A 35-year-old patient with atherosclerosis has normal LDL cholesterol but elevated lipoprotein(a). Which genetic polymorphism is primarily responsible for high Lp(a) levels?

Q.56Medium

Which of the following correctly describes the relationship between dietary cholesterol and serum LDL cholesterol?

Q.57Medium

In Gaucher disease, the accumulation of glucocerebroside occurs due to deficiency of which enzyme?

Q.58Easy

Which lipoprotein fraction is responsible for the reverse cholesterol transport from peripheral tissues to the liver?

Q.59Hard

A patient presents with neurodegenerative symptoms, progressive neuropathy, and xanthomas. Plasma cholestanol and cholestane-3-beta,5-alpha,6-beta-triol levels are markedly elevated. Which genetic defect is most likely?

Q.60Easy

Which of the following is the primary storage form of lipids in adipose tissue?