Biochemistry - MCQ Practice Questions

Which of the following lipids is amphipathic in nature and forms the structural basis of cell membranes?

A 45-year-old male presents with xanthomas and corneal arcus. Serum cholesterol is 580 mg/dL. Which lipoprotein is primarily elevated in familial hypercholesterolemia?

Beta-oxidation of a saturated fatty acid with 16 carbons produces how many acetyl-CoA molecules?

Which of the following conditions results in accumulation of sphingomyelins and cholesterol in lysosomes?

Apolipoprotein E exists in three isoforms (E2, E3, E4). Which genotype is associated with the highest risk for Alzheimer's disease?

Which of the following fatty acids is essential and must be obtained from dietary sources?

A patient with primary biliary cholangitis shows elevated cholestanol levels. Which enzyme defect is most likely responsible?

During the fed state, acetyl-CoA carboxylase (ACC) is activated by which mechanism?

Which of the following statements about lipoproteins is correct?

A patient presents with eruptive xanthomas, lipemia retinalis, and severe hypertriglyceridemia (>1500 mg/dL). Which lipoprotein fraction is predominantly elevated?

Which of the following factors would increase the fluidity of a cell membrane?

In the conversion of cholesterol to bile acids, which intermediate is formed after 7-alpha-hydroxylation?

A deficiency of apolipoprotein B-48 synthesis would primarily affect which lipid transport pathway?

Which of the following lipids serves as a precursor for the synthesis of steroid hormones and bile acids?

A 35-year-old patient with atherosclerosis has normal LDL cholesterol but elevated lipoprotein(a). Which genetic polymorphism is primarily responsible for high Lp(a) levels?

Which of the following correctly describes the relationship between dietary cholesterol and serum LDL cholesterol?

In Gaucher disease, the accumulation of glucocerebroside occurs due to deficiency of which enzyme?

Which lipoprotein fraction is responsible for the reverse cholesterol transport from peripheral tissues to the liver?

A patient presents with neurodegenerative symptoms, progressive neuropathy, and xanthomas. Plasma cholestanol and cholestane-3-beta,5-alpha,6-beta-triol levels are markedly elevated. Which genetic defect is most likely?

Which of the following is the primary storage form of lipids in adipose tissue?