Biochemistry - MCQ Practice Questions

In glycolysis, the conversion of glucose-6-phosphate to fructose-6-phosphate is catalyzed by which enzyme?

Which enzyme is the rate-limiting step of glycolysis and is inhibited by ATP and citrate?

What is the net yield of ATP from the anaerobic metabolism of one molecule of glucose?

Which of the following is a reducing sugar?

In the citric acid cycle, which carbohydrate-derived molecule enters directly after acetyl-CoA formation?

Which of the following conditions causes increased glycogenolysis in muscle tissue during exercise?

What is the primary fate of pyruvate under anaerobic conditions in muscle during intense exercise?

Which enzyme deficiency causes Pompe disease (GSD Type II)?

During the pentose phosphate pathway, which coenzyme is reduced to generate NADPH?

Which of the following best explains why glycogen is more soluble than starch despite similar glycosidic linkages?

In a patient with von Gierke disease, excessive hepatic glucose production is primarily due to:

Which of the following substrates can be directly utilized for glycogen synthesis in the liver?

A 45-year-old male presents with chronic hyperuricemia and gout. Testing reveals elevated lactic acid and hepatomegaly. Which GSD is most likely?

In the Cori cycle, lactate produced in muscle is converted to glucose in the liver. Which enzyme is crucial for the final step in hepatic gluconeogenesis?

Which adaptation occurs in skeletal muscle during prolonged fasting (>48 hours)?

A patient with G6PD deficiency may develop hemolytic anemia upon exposure to oxidative stress. This occurs because:

Which of the following correctly describes the allosteric regulation of glycogen phosphorylase in muscle?

In maple syrup urine disease (MSUD), accumulation of branched-chain amino acids affects carbohydrate metabolism by:

Which statement accurately describes the relationship between blood glucose regulation and the Warburg effect in cancer cells?

Which of the following carbohydrates is a ketohexose?