Which growth factor is primarily responsible for promoting cell proliferation in mammalian cell culture media?
Q.22Easy
What is the primary purpose of using serum-free media (SFM) in industrial cell culture?
Q.23Easy
Which of the following cell lines is commonly used for monoclonal antibody production?
Q.24Easy
The doubling time of mammalian cells cultured in vitro typically ranges between:
Q.25Medium
Which parameter is most critical for maintaining pH stability in a large-scale bioreactor?
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Q.26Medium
What is the significance of cryopreservation in cell culture banking?
Q.27Medium
In the context of Indian pharmaceutical biotech (2024-25), which cell line is most commonly used for recombinant protein production?
Q.28Medium
Which of the following best describes the G0 phase in the cell cycle?
Q.29Medium
What is the primary advantage of using suspension culture systems over adherent culture for large-scale production?
Q.30Medium
During scale-up of cell culture from 2L to 200L bioreactor, which parameter becomes increasingly challenging to maintain?
Q.31Easy
Which disinfectant is most commonly used for sterilizing bioreactor surfaces and cell culture equipment?
Q.32Medium
What is the primary function of osmolarity/osmotic pressure control in cell culture media?
Q.33Medium
In viral vaccine production using cell culture, which cell line is commonly used for influenza vaccine manufacturing?
Q.34Medium
What is the role of trypsin in cell culture preparation and maintenance?
Q.35Medium
Which of the following statements about lactate production in mammalian cell culture is correct?
Q.36Hard
What is the significance of using antifoam agents in large-scale bioreactors?
Q.37Hard
In the fed-batch culture strategy, the primary advantage over batch culture is:
Q.38Hard
Which method is most suitable for real-time monitoring of cell viability in a bioreactor during fermentation?
Q.39Hard
For Indian biotech industries (2024-25) producing therapeutic monoclonal antibodies, which regulatory requirement regarding cell line characterization is mandatory?
Q.40Hard
What is the consequence of exceeding the maximum viable cell density (MVCD) in a culture system?