Which growth factor is primarily responsible for promoting cell proliferation in mammalian cell culture media?
Q.222Easy
What is the primary purpose of using serum-free media (SFM) in industrial cell culture?
Q.223Easy
Which of the following cell lines is commonly used for monoclonal antibody production?
Q.224Easy
The doubling time of mammalian cells cultured in vitro typically ranges between:
Q.225Medium
Which parameter is most critical for maintaining pH stability in a large-scale bioreactor?
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Q.226Medium
What is the significance of cryopreservation in cell culture banking?
Q.227Medium
In the context of Indian pharmaceutical biotech (2024-25), which cell line is most commonly used for recombinant protein production?
Q.228Medium
Which of the following best describes the G0 phase in the cell cycle?
Q.229Medium
What is the primary advantage of using suspension culture systems over adherent culture for large-scale production?
Q.230Medium
During scale-up of cell culture from 2L to 200L bioreactor, which parameter becomes increasingly challenging to maintain?
Q.231Easy
Which disinfectant is most commonly used for sterilizing bioreactor surfaces and cell culture equipment?
Q.232Medium
What is the primary function of osmolarity/osmotic pressure control in cell culture media?
Q.233Medium
In viral vaccine production using cell culture, which cell line is commonly used for influenza vaccine manufacturing?
Q.234Medium
What is the role of trypsin in cell culture preparation and maintenance?
Q.235Medium
Which of the following statements about lactate production in mammalian cell culture is correct?
Q.236Hard
What is the significance of using antifoam agents in large-scale bioreactors?
Q.237Hard
In the fed-batch culture strategy, the primary advantage over batch culture is:
Q.238Hard
Which method is most suitable for real-time monitoring of cell viability in a bioreactor during fermentation?
Q.239Hard
For Indian biotech industries (2024-25) producing therapeutic monoclonal antibodies, which regulatory requirement regarding cell line characterization is mandatory?
Q.240Hard
What is the consequence of exceeding the maximum viable cell density (MVCD) in a culture system?